Brothers & Sisters is an American television drama series that centers on the Walker family and their lives in Pasadena, California. The series premiered on ABC on September 24, 2006, and aired its final episode on May 8, 2011. It aired, for its entire run, in a Sunday night timeslot after Desperate Housewives.
The cast included a collection of award-winning actors, including Sally Field, Rachel Griffiths, Calista Flockhart, Rob Lowe and Patricia Wettig. Sally Field received both a Primetime Emmy Award and a Screen Actors Guild Award for her performance throughout the series. Rachel Griffiths was also nominated for two Primetime Emmy Awards and two Golden Globe Awards for her work on the show.
In May 2011, the show completed its fifth and final season on ABC. On May 13, 2011, it was announced that ABC had decided to end the show.
The series revolves around the lives and problems of the wealthy Walker family in the wake of the death of family patriarch William Walker (Tom Skerritt), the founder of the family business Ojai Foods. The family consists of wife and mother Nora Walker (Sally Field) who must deal with revelations about her husband's infidelity, and her children Sarah (Rachel Griffiths) and Tommy (Balthazar Getty), both married executives at Ojai Foods, Kitty (Calista Flockhart), a conservative activist, Kevin (Matthew Rhys), a gay lawyer, and youngest sibling Justin (Dave Annable), who has recently returned from the Iraq War with a substance abuse problem. They were joined by Nora's brother Saul (Ron Rifkin) and Holly Harper (Patricia Wettig), William's mistress. Plotlines typically revolved around the romantic relationships of the family, their business fortunes, especially with regard to the control of Ojai Foods, and the relationship between the siblings. Most conflicts were resolved with a renewed call for family unity.
The show's narrative launched with the death of William Walker at Kitty's birthday party. His death causes a number of secrets from his life to be revealed—secrets that impact the remainder of his family and which include the introduction of William's mistress Holly Harper and her daughter Rebecca.
Other main storylines throughout the series include the personal, political (usually through Robert and Kitty's and later Kevin's careers) and professional lives of Nora and all the brothers and sisters; their relationships with each other; interaction with Rebecca and her mother (William's mistress) Holly; and the running of the family business Ojai Foods—which is mostly looked after by Saul, Sarah and Tommy along with Holly and Rebecca from season 3 onwards. After the family sells Ojai Foods, Scotty and Saul open a restaurant and Nora begins working at a radio station which Sarah decides to buy.
- Nora Walker, widow of William Walker, mother of Sarah, Kitty, Tommy, Kevin and Justin; Grandmother to Paige, Cooper, Evan, Elizabeth, William Jr ,(Deceased), Olivia and Daniel; home maker.
- Sarah Laurent, daughter of Nora Walker and Nick Brody; mother of Paige and Cooper; President of Ojai Foods and former CEO of Greenotopia; ex-wife of Joe Whedon and wife of Luc Laurent.
- Kitty Walker, daughter of Nora and William Walker, one year younger than Sarah; adoptive mother of Evan; writer and former communication director, television and radio host; widow of Robert McCallister.
- Tommy Walker, son of Nora and William Walker, two years younger than Kitty; father of Elizabeth and William Jr (Deceased); former president of Ojai Foods; ex-husband to Julia Ridge and fiancé of Rose.
- Kevin Walker, son of Nora and William Walker, one year younger than Tommy; adoptive father of Olivia; father of Daniel; surrogate father of Elizabeth and William Jr (Deceased); pro bono lawyer and former communications director and corporate lawyer; husband of Scotty Wandell.
- Justin Walker, son of Nora and William Walker; ten years younger than Kevin; paramedic, war veteran and former med school student; former alcoholic and drug addict; ex-husband of Rebecca Harper.
- Julia Ridge, ex-wife of Tommy Walker; mother of Elizabeth; teacher.
- Joe Whedon, ex-husband of Sarah Walker; father of Gabe, Paige and Cooper; music teacher.
- Saul Holden, brother of Nora Walker; restaurant owner and former CFO of Ojai Foods; fiancé of Jonathan Byrold.
- Holly Harper, ex-mistress of William Walker; mother of Rebecca; former chairwoman and CEO of Ojai Foods and actress; fiancée of David Caplan.
- Rebecca Harper, daughter of Holly Harper; former advertising executive at Ojai Foods; ex-wife of Justin Walker.
- Paige Whedon, daughter of Sarah Walker and Joe Whedon.
- Cooper Whedon, son of Sarah Walker and Joe Whedon.
- Robert McCallister, deceased husband of Kitty Walker; father of Sophie and Jack and adoptive father of Evan; former Senator of California; ex-husband of Courtney McCallister.
- Scotty Wandell, husband of Kevin Walker; father of Daniel and adoptive father of Olivia; restaurant owner and head chef.
- Ryan Lafferty, son of William Walker and Connie Lafferty; former employee at Ojai Foods.
- Luc Laurent, husband of Sarah Walker; painter and former underwear model.
|Dave Annable||Justin Walker||Main|
|Sally Field||Nora Walker||Main|
|Calista Flockhart||Kitty Walker||Main|
|Rachel Griffiths||Sarah Laurent||Main|
|Matthew Rhys||Kevin Walker||Main|
|Ron Rifkin||Saul Holden||Main|
|Patricia Wettig||Holly Harper||Main|
|Emily VanCamp||Rebecca Harper||Main||Guest|
|Balthazar Getty||Tommy Walker||Main||Guest|
|Kerris Dorsey||Paige Whedon||Main||Recurring|
|Sarah Jane Morris||Julia Walker||Main||Guest|
|John Pyper-Ferguson||Joe Whedon||Main||Recurring|
|Rob Lowe||Robert McCallister||Recurring||Main|
|Maxwell Perry Cotton||Cooper Whedon||Recurring||Main||Recurring|
|Luke Macfarlane||Scotty Wandell||Recurring||Main|
|Luke Grimes||Ryan Lafferty||Guest||Main|
|Gilles Marini||Luc Laurent||Guest||Main|
|John Apicella||Frank||Season 5|
|Amy Aquino||Dr. Joan Avadon||Season 4|
|Beau Bridges||Nick Brody||Season 5|
|Max Burkholder||Jack McCallister||Season 1, 2, 3|
|Luc Charbonnier||Ben Tyler||Season 3|
|Richard Chamberlain||Jonathan Byrold||Season 5|
|Peter Coyote||Mark August||Season 1|
|Jeremy Davidson||Jack Randall||Season 5|
|Ryan Devlin||Seth Whitley||Season 5|
|Marika Dominczyk||Tyler Altamirano||Season 1, 5|
|Justine Dorsey||Sophie McCallister||Season 1, 2, 3|
|Edwina Findley||Jill||Season 5|
|Peter Gerety||Dennis York||Season 4|
|Danny Glover||Isaac Marshall||Season 2|
|Nigel Havers||Roger Grant||Season 3, 4|
|Josh Hopkins||Warren Salter||Season 1|
|Jay Karnes||Roy Scovell||Season 4|
|Matt Letscher||Alec Tyler||Season 3, 4|
|Jason Lewis||Chad Barry||Season 1, 3|
|Will McCormack||Ethan Tavis||Season 3|
|Denis O'Hare||Travis March||Season 2, 4|
|Ken Olin||David Caplan||Season 2, 3, 4, 5|
|Roxy Olin||Michelle McCormack||Season 1, 4, 5|
|Eric Christian Olsen||Kyle DeWitt||Season 3|
|Tyler Posey||Gabe Whedon||Season 1|
|Keri Lynn Pratt||Amber Trachtenberg||Season 1|
|Isabella Rae Thomas||Olivia||Season 5|
|Emily Rose||Lena Branigan||Season 2|
|Matthew Settle||Jonathan Sellers||Season 1|
|Tom Skerritt||William Walker||Season 1, 2, 3, 4|
|Sonja Sohn||Trish Evans||Season 3|
|Jon Tenney||Simon Craig||Season 4|
|John Terry||Karl West||Season 5|
|Steven Weber||Graham Finch||Season 2, 3|
|Treat Williams||David Morton||Season 1|
|Eric Winter||Jason McCallister||Season 1, 2|
|Odette Yustman||Annie Miller||Season 5|